IP3 receptor (IP3R)-mediated Ca2+ transfer at the mitochondria-endoplasmic reticulum (ER) contact sites (MERCS) drives mitochondrial Ca2+...
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T-type Ca2+ channels mediate intrinsic neuronal oscillations and rhythmic burst spiking, and facilitate the generation of tremor rhythms in motor circuits.
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Here, we develop photocatalyst-based metal-organic frameworks (DCSA-MOFs) to modulate Ca 2+ responses in cells, multicellular spheroids, and organs.
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Early in Alzheimer's disease (AD), pericytes constrict capillaries, increasing their hydraulic resistance and trapping of immune cells and,...
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The mitochondrial Ca2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation ... Introduction: The mitochondrial...
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Action potentials trigger neurotransmitter release at the presynaptic active zone with spatiotemporal precision.
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The central role of Ca 2+ dysregulation in age-related memory deficits and neurodegenerative disease, proposed more than 30 years ago.
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Here we identify bona fide cell surface hypo-osmosensors in Arabidopsis and find that pollen Ca 2+ spiking is controlled directly by water through these hypo-...
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Our findings uncover the key steps of a previously unappreciated mechanism utilized by mammalian cells to finetune their calcium signaling regulation through...
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This study demonstrates that CD38 affects calcium homeostasis in CD4 + T cells by controlling cell membrane lipid composition that results in suppressed IL-2...
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