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channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia
Nature
Early in Alzheimer's disease (AD), pericytes constrict capillaries, increasing their hydraulic resistance and trapping of immune cells and,...
1 месяц назад
Optogenetic β cell interrogation in vivo reveals a functional hierarchy directing the Ca
Science | AAAS
We reveal a hierarchy of cells, each with a different level of influence over islet-wide Ca 2+ dynamics. First-responder β cells lie at the top of the...
4 месяца назад
Overload Combined with Chemodynamic Therapy to Enhance Cancer Immunotherapy
ACS Publications
The Ca2+ from CaO2 NPs and the elevated level of endogenous Ca2+ induced by CUR trigger Ca2+ overload and mediate apoptosis in tumor cells. The...
4 недели назад
The potential roles of T-type Ca2+ channels in motor coordination
Frontiers
T-type Ca2+ channels mediate intrinsic neuronal oscillations and rhythmic burst spiking, and facilitate the generation of tremor rhythms in motor circuits.
4 месяца назад
-Storage Chemistries by Hetero-Solvation Electrolyte toward High-Voltage Ca
Wiley Online Library
Via hybrid electrolytes with [Ca2+(H2O)(acetonitrile)(CF3SO3)−] hetero-solvation unit, a new Ca2+-based hybrid battery is established by...
2 недели назад
Guard cells count the number of unitary cytosolic Ca2+ signals to regulate stomatal dynamics
ScienceDirect.com
Our data reveal that guard cells are capable of counting Ca 2+ transients in order to optimize stomatal aperture in the prevailing environmental conditions.
3 недели назад
A molecular mechanism to diversify Ca2+ signaling downstream of Gs protein-coupled receptors
Nature
Our findings uncover the key steps of a previously unappreciated mechanism utilized by mammalian cells to finetune their calcium signaling regulation through...
2 месяца назад
signaling for regulating cellular and animal behaviors via MOF-enabled H
Science | AAAS
Here, we develop photocatalyst-based metal-organic frameworks (DCSA-MOFs) to modulate Ca 2+ responses in cells, multicellular spheroids, and organs.
6 месяцев назад
in the dorsal striatum suppresses neuronal activity to oppose cue-induced reinstatement of cocaine seeking
Frontiers
Astrocyte Ca2+ in the dorsal striatum suppresses neuronal activity to oppose cue-induced reinstatement of cocaine seeking ... Recent literature...
2 месяца назад
Mitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division
ScienceDirect.com
Depletion of LBR disrupts the Ca 2+ influx surge, reduces ATP production, and postpones the metaphase-anaphase transition and subsequent cell division.
1 месяц назад