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6 дней назад · TRPML1 is a lysosomal ROS-sensitive Ca2+ channel that regulates lysosomal trafficking and biogenesis. Small-molecule agonists of TRPML1 prevented PA-induced ...
15 окт. 2024 г. · Neuronal Ca2+ signals can affect excitability and neural circuit formation. Ca2+ signals are modified by Ca2+ flux from intracellular stores as well as the ...
2 нояб. 2024 г. · This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells.
15 окт. 2024 г. · The resulting new cameleons permit Ca2+ measurements despite significant cytosolic acidification. When Ca2+ is elevated, the CaM and CaM-binding peptide fused ...
21 окт. 2024 г. · The increased ER-to-mitochondria Ca2+ transfer is essential for enhancing mitochondrial ATP production, which supports the high energy demand during mitosis.
15 окт. 2024 г. · The Ca2+ from CaO2 NPs and the elevated level of endogenous Ca2+ induced by CUR trigger Ca2+ overload and mediate apoptosis in tumor cells. The H2O2 released ...
27 окт. 2024 г. · Where is calcium stored in the cell? What is the role of the endoplasmic reticulum? When are calcium ion-gated channels used?
19 окт. 2024 г. · We find that incoming vesicle fusion is a prerequisite for lysosomal Ca 2+ efflux that leads to acidification and hydrolytic enzyme activation.
21 окт. 2024 г. · This study assessed the effect of oxatomide on cell viability and intracellular free Ca2+ concentrations ([Ca2+]i) and examined whether oxatomide-induced ...