... Ca2+ mobilization and Ca2+ entry mechanisms coupled to the α mesenteric 1 -adrenoceptor arteries in were resistance kept in a arteries, nominally endothelium-denuded Ca2+-free medium, stimulated with PE and further activated with ...
... Ca2+] i may be regulated independently, Ca2+ waves generated in the cytoplasm can spread into the nucleo- plasm of several cell types. Furthermore, cytoplasmic Ca2+puffs can cause transient increase in nucleoplas- mic [Ca2+]. In HeLa ...
... Ca2+ pool contributes to whole-cell intracellular Ca2+ transients in human iPSC-CMs (Itzhaki et al., 2011). To maintain sustainable Ca2+ cycling, released Ca2+ must be removed from the cytosol. In adult human CMs, 70% of cytosolic ...
... Ca2+], and to a lesser extent on factors that affect Ca2+ sensitivity of the contractile apparatus. The contractility of cardiac muscle is primarily dependent on the way that the cell handles Ca2+. Initiation. of. contraction. During the ...
This book will be informative and challenging for scientists, enlightening and stimulating for intellectuals and serious students, and highly beneficial and interesting for Alzheimer’s workers and the public.
... Ca2+ in the presynaptic nerve terminal. Thus, understanding presynaptic Ca2+ signaling and the way in which Ca2+ triggers transmitter release are important prerequisites for understand- ing the mechanisms underlying STE. Presynaptic. Ca2 ...
... Ca2+ in a multi-chromatic manner. Accordingly, we co-expressed each sub-mitochondrial targeted GEM-GeCO1 with either the cytosolic- (CARGeCO1) or the mitochondrial matrix-targeted (mt-CARGeCO1) red Ca2+ biosensor and imaged the ...
... Ca2+ signaling and the way in which Ca2+ triggers transmitter release are important prerequisites for understand- ing the mechanisms underlying STE. Presynaptic. Ca2+signaling: phasic. release. The briefest form of Ca2+ signaling in the ...
... Ca2+ acts as a switch for these enzymes. Physiologically bulk cytosolic Ca2+ in non-muscle cells rarely rises more than 1–2 μM. So it is perhaps surprising to find that the calpain-1 is activated by Ca2+ at 20–60 μM Ca2+ and calpain ...
... Ca2+ concentration ([Ca2+] i ) (15), but important differences were noted. FcγRIIa used the second messenger of Ca2+ from an internal pool (15), while IP3 to the increase induce release in [Ca2+] i induced by FcγRIIIb did not involve ...