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... Ca2+ response. 2. Results 2.1. Stromal Interaction Molecule 1 (STIM1) Knockout Represses Store-Operated Ca2+ Entry (SOCE) in Mouse Embryonic Fibroblasts (MEF) Cells In order to investigate the effect of STIM1 on SOCE, wild-type (MEF-WT) ...
... Ca2+ Flux as the Second Messenger of P. edulis under Heterogeneous Water Stress NMT was used to monitor Ca2+ flux in the pileorhiza, mesophyll transverse section, and rhizome transverse section in vivo, the flux rule is shown in Figure ...
... Ca2+ entry points in the neuronal architecture, expressing both preand postsynaptic Ca2+ channels/receptors, including presynaptic RyRs, N/P/Q voltage gated Ca2+ channels (VGCCs), α7 nicotinic acetylcholine receptors (α7 nAChRs), and ...
... Ca2+ level recovery mechanisms involved in this process. The mRNA and protein expression levels of PMCA3 (a major plasma membrane Ca2+ ATPase in skeletal muscle) were first detected. The results showed that, compared with the SA and PRE ...
... Ca2+ (thus increasing Ca2+ sensitivity). The model parameters and changes introduced to simulate the effects of the Tpm mutations listed above are described in Supplementary Materials Table S4. The resulting dependencies of isometric ...
... Ca2+ [reviewed by Richter and Kass (8)]. Mitochondria take up and release Ca2+ by separate routes. As a consequence, Ca2* is cycled across their inner membranes (7). Mitochondria are of central importance for physiologic Ca2+ handling ...
... Ca2+ homeostasis is critical for normal cellular function, particularly for cardiomyocytes, and may be dysregulated in early atrial myopathy. Store-operated Ca2+ entry (SOCE) is recognized to coexist with voltage-gated Ca2+ channels ...
... Ca2+ release in the process of FSE-mediated GLUT4 translocation and the increase in intracellular Ca2+ levels. To support this hypothesis, we used 100 μM 2-APB to block IP3R-regulated intracellular Ca2+ release. We found that 2-APB ...
... Ca2+] ([Ca2+] i ) (see description in the text). In salivary gland acinar cells, IP3 -mediated Ca2+ release occurs primarily via IP3R2 and -3 [4,5]. Importantly, the resulting decrease in ER-[Ca2+] triggers the activation of Ca2+ influx ...
... Ca2+ signals propagate inside the cells. To this end, Ca2+ release from the endoplasmic reticulum into the cytosol through IP3 Rs are Ca2+ channels whose open probability depends on the cytosolic Ca2+ concentration. Therefore, the ...