Mitochondrial calcium (mCa2+) has a central role in both metabolic regulation and cell death signalling, however its role in homeostatic...
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Mitochondrial Ca²⁺ accumulation stimulates aerobic metabolism by inducing the activity of three TCA cycle dehydrogenases. In detail, matrix Ca²⁺ indirectly...
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Calcium–lipid electrostatic interactions are shown to amplify the tyrosine phosphorylation of CD3ε and CD3ζ in T-cell antigen receptor...
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Genetic deletion of the lysosomal Ca2+ channel MCOLN1 in mice results in muscular dystrophy, implicating this source of calcium in muscle...
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During myelination, individual oligodendrocytes initially over-produce short myelin sheaths, which are either retracted or stabilized.
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IP3 receptors (IP3Rs) release Ca2+ from the ER when they bind IP3 and Ca2+. The spatial organization of IP3Rs determines both the...
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A subpopulation of cholinergic 3 neurons triggers Ca 2+ currents among intestinal epithelial cells, the enterocytes, to promote return to homeostasis.
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This review will outline general aspects of neuronal Ca 2+ signalling, introduce the members of the NCS family and summarize their individual properties and...
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Ca²⁺ antagonist drugs are widely used in therapy of cardiovascular disorders. Three chemical classes of drugs bind to three separate,...
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Ca2+ signals control cell migration by regulating forward movement and cell adhesion. However, it is not well understood how Ca2+-regulatory...
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