Early in Alzheimer's disease (AD), pericytes constrict capillaries, increasing their hydraulic resistance and trapping of immune cells and,...
4 ìåñÿöà íàçàä

Here, we discuss current research into mitochondrial Ca 2+ regulatory machineries and how mitochondrial Ca 2+ dysregulation contributes to brain aging and...
6 ìåñÿöåâ íàçàä

Depletion of LBR disrupts the Ca 2+ influx surge, reduces ATP production, and postpones the metaphase-anaphase transition and subsequent cell division.
2 ìåñÿöà íàçàä

We engineered a nanoplatform based on CaO 2 nanoparticles (NPs) capable of encapsulating curcumin (CUR) and self-supplying H 2 O 2 for synergistic CDT-...
3 ìåñÿöà íàçàä

We show that the Rab-GTPase activating protein AS160 is a lipid-responsive regulator of Ca 2+ homeostasis through governing lysophosphatidylinositol metabolism...
2 ìåñÿöà íàçàä

AD neurons exhibit enhanced intracellular calcium (Ca 2+ ) liberation from the endoplasmic reticulum (ER) and reduced store-operated Ca 2+ entry (SOC).
6 ìåñÿöåâ íàçàä

A viable strategy was proposed to control calcification by adjusting a mild acidic condition in an anaerobic reactor without hindering organic degradation.
6 ìåñÿöåâ íàçàä

Our findings uncover ABA–Ca 2+ –CPK signalling that modulates root cap cycle plasticity in adaptation to adverse environments.
1 ìåñÿö íàçàä

We provide evidence that IHCs autonomously generate single fCaTs and minibursts whereas bursts synchronized between neighboring IHCs were mostly triggered by...
6 ìåñÿöåâ íàçàä

We find that spaceflight induces significant soleus muscle atrophy and SR Ca 2+ leak that cannot be counteracted with BuOE treatment.
5 ìåñÿöåâ íàçàä