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signaling to promote root hair growth in Arabidopsis
Nature
Cyclic nucleotide-gated channel 5 (CNGC5), CNGC6, and CNGC9 (CNGC5/6/9 for simplicity) control Arabidopsis root hair (RH) growth by...
3 дня назад
Dysfunction of Mitochondrial Ca2+ Regulatory Machineries in Brain Aging and Neurodegenerative Diseases
Frontiers
Here, we discuss current research into mitochondrial Ca 2+ regulatory machineries and how mitochondrial Ca 2+ dysregulation contributes to brain aging and...
6 месяцев назад
Mitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division
ScienceDirect.com
Depletion of LBR disrupts the Ca 2+ influx surge, reduces ATP production, and postpones the metaphase-anaphase transition and subsequent cell division.
2 месяца назад
channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia
Nature
Early in Alzheimer's disease (AD), pericytes constrict capillaries, increasing their hydraulic resistance and trapping of immune cells and,...
4 месяца назад
in the dorsal striatum suppresses neuronal activity to oppose cue-induced reinstatement of cocaine seeking
Frontiers
The dorsal striatum, specifically, is known to play a role in reward processing with neuronal activity that can be influenced by astrocyte Ca<sup>2+</sup>.
4 месяца назад
Simultaneous detection of membrane contact dynamics and associated Ca
Nature
Membrane contact sites (MCSs) are hubs allowing various cell organelles to coordinate their activities. The dynamic nature of these sites...
2 месяца назад
ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca
Nature
IP3 receptor (IP3R)-mediated Ca2+ transfer at the mitochondria-endoplasmic reticulum (ER) contact sites (MERCS) drives mitochondrial Ca2+...
3 месяца назад
activity in the pre-hearing mammalian cochlea
Nature
The refinement of neural circuits towards mature function is driven during development by patterned spontaneous calcium-dependent electrical...
2 недели назад
homeostasis by controlling lysophosphatidylinositol metabolism and signaling
Nature
We show that the Rab-GTPase activating protein AS160 is a lipid-responsive regulator of Ca 2+ homeostasis through governing lysophosphatidylinositol metabolism...
2 месяца назад
channel clustering and vesicle priming at hippocampal synapses
Nature
We conclude that active zones consist of distinct machineries to organize Ca V 2s and prime vesicles, and Liprin-α and PTPσ specifically support priming site...
4 месяца назад