Ca2+ - �� Google

channels in Alzheimer�s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia

Early in Alzheimer's disease (AD), pericytes constrict capillaries, increasing their hydraulic resistance and trapping of immune cells and,...
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Dysfunction of Mitochondrial Ca2+ Regulatory Machineries in Brain Aging and Neurodegenerative Diseases

Here, we discuss current research into mitochondrial Ca 2+ regulatory machineries and how mitochondrial Ca 2+ dysregulation contributes to brain aging and...
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Light-sensitive Ca2+ signaling in the mammalian choroid

As a key second messenger and regulator of vasculature function, Ca2+ dynamics in endothelial cells and mural cells of the choroid could be key targets of light...
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Bypassing Ca2+ Influx for Antimetastasis Photodynamic Therapy via Robust Nucleus-Targeted Near-Infrared Cyanines

ACS Publications

Hypoxia-induced tumor metastasis severely hinders the efficacy of photodynamic therapy (PDT) in cancer treatment.
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Simultaneous detection of membrane contact dynamics and associated Ca

Membrane contact sites (MCSs) are hubs allowing various cell organelles to coordinate their activities. The dynamic nature of these sites...
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The potential roles of T-type Ca2+ channels in motor coordination

T-type Ca2+ channels mediate intrinsic neuronal oscillations and rhythmic burst spiking, and facilitate the generation of tremor rhythms in motor circuits.
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Overload Combined with Chemodynamic Therapy to Enhance Cancer Immunotherapy

ACS Publications

We engineered a nanoplatform based on CaO 2 nanoparticles (NPs) capable of encapsulating curcumin (CUR) and self-supplying H 2 O 2 for synergistic CDT-...
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Modulation of Ca2+ oscillation following ischemia and nicotinic acetylcholine receptors in primary cortical neurons by high-throughput analysis | Scientific Reports

Ischemia for 1 and 2 h resulted in an increase in the frequency of Ca 2+ oscillations and a decrease in their amplitude in a time-dependent manner.
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Waves of Inner Supporting Cells in the Developing Mouse Cochlea

We provide evidence that IHCs autonomously generate single fCaTs and minibursts whereas bursts synchronized between neighboring IHCs were mostly triggered by...
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homeostasis by controlling lysophosphatidylinositol metabolism and signaling

We show that the Rab-GTPase activating protein AS160 is a lipid-responsive regulator of Ca 2+ homeostasis through governing lysophosphatidylinositol metabolism...
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