Investigators of Ca2+ dynamics and brain dysfunction especially will find this book useful in the development of novel drugs to treat neuropsychiatric diseases.
This book is designed for laboratory use by graduate students, technicians, and researchers in many disciplines, ranging from molecular to cellular levels of investigation.
The definitive text on the key component for cell functions—intracellular calcium This comprehensive book reveals the evidence for intracellular calcium as a universal switch in all animal, plant, fungal and microbial cells.
Calcium in Living Cells will update classic techniques in detecting microscopic levels of calcium ions (Ca2+) in living cells, as well as address new techniques in the field of calcium detection and calcium signaling.
... Ca2+]I in little neurons is more noteworthy in db/db mice (type 2 diabetes model). There was no distinction in [Ca2+]I in huge neurons in the two mouse models. In another examination in Wistar-diabetic mice with STZ 8–14 weeks there ...
... Ca2+: The Final Signal of Electrical Activity and Regulator of Ion Channels 189 Unique Features of Ca2+ as a Signaling Ion in Myocytes Translating Changes in Ca2+ into a Cellular Response: CaM as the Prototypical Cardiac Ca2+ Sensor 189 ...
... Ca2+ load on excitation- contraction (E- C) coupling efficacy and diastolic SR Ca2+ leak current. (A) Voltage- clamp in rabbit ventricular myocyte where SR Ca2+ load was varied by prepulse protocols and caffeine- induced SR Ca2+ ...
... Ca2+ fluxes at different stimulation frequencies. As mentioned above, we were able to do this using a spectrofluorometric system (see section “Fluorometric Measurements in Live Myocytes”). Cells were super-fused with 1.5 mM Ca2+ ...